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1

Management of HCV patients in cases of direct-acting antiviral failure

Hayes, C. Nelson, Imamura, Michio, Chayama, Kazuaki

Journal:

Expert Review of Gastroenterology and Hepatology

Year:

2019

Language:

english

File:

PDF, 1.01 MB

english, 2019

2

Impact of viral amino acid substitutions and host interleukin-28b polymorphism on replication and susceptibility to interferon of hepatitis C virus

Nobuhiko Hiraga, Hiromi Abe, Michio Imamura, Masataka Tsuge, Shoichi Takahashi, C. Nelson Hayes, Hidenori Ochi, Chise Tateno, Katsutoshi Yoshizato, Yusuke Nakamura, Naoyuki Kamatani, Kazuaki Chayama

Journal:

Year:

2011

Language:

english

File:

PDF, 300 KB

english, 2011

3

Inverse association of IL28B genotype and liver mRNA expression of genes promoting or suppressing antiviral state

Hiromi Abe, C. Nelson Hayes, Hidenori Ochi, Masataka Tsuge, Daiki Miki, Nobuhiko Hiraga, Michio Imamura, Shoichi Takahashi, Michiaki Kubo, Yusuke Nakamura, Naoyuki Kamatani, Kazuaki Chayama

Journal:

Journal of Medical Virology

Year:

2011

Language:

english

File:

PDF, 427 KB

english, 2011

4

Factors predictive of sustained virological response following 72 weeks of combination therapy for genotype 1b hepatitis C

Kazuaki Chayama, C. Nelson Hayes, Kentaro Yoshioka, Hisataka Moriwaki, Takashi Okanoue, Shotaro Sakisaka, Tetsuo Takehara, Makoto Oketani, Joji Toyota, Namiki Izumi, Yoichi Hiasa, Akihiro Matsumoto, H

Journal:

Journal of Gastroenterology

Year:

2011

Language:

english

File:

PDF, 426 KB

english, 2011

5

Animal model for study of human hepatitis viruses

Kazuaki Chayama, C Nelson Hayes, Nobuhiko Hiraga, Hiromi Abe, Masataka Tsuge, Michio Imamura

Journal:

Journal of Gastroenterology and Hepatology

Year:

2011

Language:

english

File:

PDF, 532 KB

english, 2011

6

Hepatitis C virus: How genetic variability affects pathobiology of disease

Kazuaki Chayama, C Nelson Hayes

Journal:

Journal of Gastroenterology and Hepatology

Year:

2011

Language:

english

File:

PDF, 920 KB

english, 2011

7

Genetics of IL28B and HCV—response to infection and treatment

Hayes, C. Nelson, Imamura, Michio, Aikata, Hiroshi, Chayama, Kazuaki

Journal:

Nature Reviews Gastroenterology and Hepatology (formerly Nature Clinical Practice Gastroenterology and Hepatology)

Year:

2012

Language:

english

File:

PDF, 744 KB

english, 2012

8

Hepatocellular carcinoma: Towards personalized medicine

Daiki Miki, Hidenori Ochi, C. Nelson Hayes, Hiroshi Aikata, Kazuaki Chayama

Journal:

Year:

2012

Language:

english

File:

PDF, 265 KB

english, 2012

9

Impact of interleukin-28B genotype on in vitro and in vivo systems of hepatitis C virus replication

Kazuaki Chayama, C. Nelson Hayes, Michio Imamura

Journal:

Hepatology Research

Year:

2012

Language:

english

File:

PDF, 769 KB

english, 2012

10

A single nucleotide polymorphism in activated cdc42 associated tyrosine kinase 1 influences the interferon therapy in hepatitis C patients

Yoshifumi Fujimoto, Hidenori Ochi, Toshiro Maekawa, Hiromi Abe, C. Nelson Hayes, Hiromitsu Kumada, Yusuke Nakamura, Kazuaki Chayama

Journal:

Journal of Hepatology

Year:

2011

Language:

english

File:

PDF, 1.34 MB

english, 2011

11

Accumulation of refractory factors for pegylated interferon plus ribavirin therapy in older female patients with chronic hepatitis C

Kazuaki Chayama, C. Nelson Hayes, Kentaro Yoshioka, Hisataka Moriwaki, Takeshi Okanoue, Shotaro Sakisaka, Tetsuo Takehara, Makoto Oketani, Joji Toyota, Namiki Izumi, Yoichi Hiasa, Akihiro Matsumoto, H

Journal:

Hepatology Research

Year:

2010

Language:

english

File:

PDF, 986 KB

english, 2010

12

Treatment of chronic hepatitis C virus infection in Japan: update on therapy and guidelines

Kazuaki Chayama, C. Nelson Hayes, Waka Ohishi, Yoshiiku Kawakami

Journal:

Journal of Gastroenterology

Year:

2013

Language:

english

File:

PDF, 940 KB

english, 2013

13

ITPA Polymorphism Affects Ribavirin-Induced Anemia and Outcomes of Therapy—A Genome-Wide Study of Japanese HCV Virus Patients

Hidenori Ochi, Toshiro Maekawa, Hiromi Abe, Yasufumi Hayashida, Rikita Nakano, Michaki Kubo, Tatsuhiko Tsunoda, C. Nelson Hayes, Hiromitsu Kumada, Yusuke Nakamura, Kazuaki Chayama

Journal:

Gastroenterology

Year:

2010

Language:

english

File:

PDF, 1.30 MB

english, 2010

14

Response to “Treatment guidelines for HCV genotype 1: mono for low, triple for high, and dual for ‘middle’?”

Kazuaki Chayama, C. Nelson Hayes, Waka Ohishi…

Journal:

Journal of Gastroenterology

Year:

2013

Language:

english

File:

PDF, 101 KB

english, 2013

15

Optimizing triple therapy and IFN/RBV-free regimens for hepatitis C virus infection

Chayama, Kazuaki, Mitsui, Fukiko, Hayes, C Nelson

Journal:

Expert Review of Gastroenterology and Hepatology

Year:

2015

Language:

english

File:

PDF, 516 KB

english, 2015

16

Interleukin-28B polymorphisms and hepatitis C virus clearance

Kazuaki Chayama,C Nelson Hayes

Journal:

Genome Medicine

Year:

2013

Language:

english

File:

PDF, 104 KB

english, 2013

17

A Translational Study of Resistance Emergence Using Sequential Direct-Acting Antiviral Agents for Hepatitis C Using Ultra-Deep Sequencing

Abe, Hiromi, Hayes, C Nelson, Hiraga, Nobuhiko, Imamura, Michio, Tsuge, Masataka, Miki, Daiki, Takahashi, Shoichi, Ochi, Hidenori, Chayama, Kazuaki

Journal:

American Journal of Gastroenterology

Year:

2013

Language:

english

File:

PDF, 567 KB

english, 2013

18

Emerging treatments for chronic hepatitis C

Hayes, C. Nelson, Chayama, Kazuaki

Journal:

Journal of the Formosan Medical Association

Year:

2015

Language:

english

File:

PDF, 556 KB

english, 2015

19

New insight into the enhanced effect of pegylated interferon-α

Abe, Hiromi, Hayes, C. Nelson, Chayama, Kazuaki

Journal:

Year:

2014

Language:

english

File:

PDF, 1.19 MB

english, 2014

20

Novel Robust in Vitro Hepatitis B Virus Infection Model Using Fresh Human Hepatocytes Isolated from Humanized Mice

Ishida, Yuji, Yamasaki, Chihiro, Yanagi, Ami, Yoshizane, Yasumi, Fujikawa, Kazuyuki, Watashi, Koichi, Abe, Hiromi, Wakita, Takaji, Hayes, C. Nelson, Chayama, Kazuaki, Tateno, Chise

Journal:

The American Journal of Pathology

Year:

2015

Language:

english

File:

PDF, 1.88 MB

english, 2015

21

A Nonsynonymous Polymorphism in Semaphorin 3A as a Risk Factor for Human Unexplained Cardiac Arrest with Documented Ventricular Fibrillation

Nakano, Yukiko, Chayama, Kazuaki, Ochi, Hidenori, Toshishige, Masaaki, Hayashida, Yasufumi, Miki, Daiki, Hayes, C. Nelson, Suzuki, Hidekazu, Tokuyama, Takehito, Oda, Noboru, Suenari, Kazuyoshi, Uchimu

Journal:

Year:

2013

Language:

english

File:

PDF, 1.82 MB

english, 2013

22

HBV culture and infectious systems

Hayes, C. Nelson, Chayama, Kazuaki

Journal:

Hepatology International

Year:

2016

Language:

english

File:

PDF, 1.09 MB

english, 2016

23

Hepatitis C virus treatment update — A new era of all-oral HCV treatment

Chayama, Kazuaki, Imamura, Michio, Hayes, C. Nelson

Journal:

Advances in Digestive Medicine

Year:

2016

Language:

english

File:

PDF, 1.36 MB

english, 2016

24

Daclatasvir and asunaprevir treatment improves liver function parameters and reduces liver fibrosis markers in chronic hepatitis C patients

Miyaki, Eisuke, Imamura, Michio, Hiraga, Nobuhiko, Murakami, Eisuke, Kawaoka, Tomokazu, Tsuge, Masataka, Hiramatsu, Akira, Kawakami, Yoshiiku, Aikata, Hiroshi, Hayes, C. Nelson, Chayama, Kazuaki

Journal:

Hepatology Research

Year:

2016

Language:

english

File:

PDF, 481 KB

english, 2016

25

Early events in hepatitis B virus infection: From the cell surface to the nucleus

Hayes, C Nelson, Zhang, Yizhou, Makokha, Grace Naswa, Hasan, Md Zobaer, Omokoko, Magot D, Chayama, Kazuaki

Journal:

Journal of Gastroenterology and Hepatology

Year:

2016

Language:

english

File:

PDF, 453 KB

english, 2016

26

Pan-genotypic cell culture system for propagation of hepatitis C virus clinical isolates

Abe-Chayama, Hiromi, Hayes, C. Nelson, Chayama, Kazuaki

Journal:

Year:

2016

Language:

english

File:

PDF, 802 KB

english, 2016

27

Interferon stimulated genes and innate immune activation following infection with hepatitis B and C viruses

Hayes, C. Nelson, Chayama, Kazuaki

Journal:

Journal of Medical Virology

Year:

2016

Language:

english

File:

PDF, 740 KB

english, 2016

28

Treatment of HCV patients on hemodialysis with daclatasvir and asunaprevir

Chayama, Kazuaki, Hayes, Clair Nelson

Journal:

Journal of Gastroenterology

Year:

2017

Language:

english

File:

PDF, 326 KB

english, 2017

29

Hepatitis C Virus (HCV) Reactivation Caused by Steroid Therapy for Dermatomyositis

Mori, Nami, Imamura, Michio, Takaki, Shintaro, Araki, Takehisa, Hayes, Nelson C., Aisaka, Yasuyuki, Chayama, Kazuaki

Journal:

Internal Medicine

Year:

2014

Language:

english

File:

PDF, 1.26 MB

english, 2014

30

The practical management of chronic hepatitis C infection in Japan - dual therapy of daclatasvir + asunaprevir

Hayes, C. Nelson, Imamura, Michio, Chayama, Kazuaki

Journal:

Expert Review of Gastroenterology and Hepatology

Year:

2017

Language:

english

File:

PDF, 1.21 MB

english, 2017

31

Why highly effective drugs are not enough: the need for an affordable solution to eliminating HCV

Hayes, C. Nelson, Chayama, Kazuaki

Journal:

Expert Review of Clinical Pharmacology

Year:

2017

Language:

english

File:

PDF, 710 KB

english, 2017

32

Retrospective Identification of Herpes Simplex 2 Virus-Associated Acute Liver Failure in an Immunocompetent Patient Detected Using Whole Transcriptome Shotgun Sequencing

Ono, Atsushi, Hayes, C. Nelson, Akamatsu, Sakura, Imamura, Michio, Aikata, Hiroshi, Chayama, Kazuaki

Journal:

Case Reports in Hepatology

Year:

2017

Language:

english

File:

PDF, 4.74 MB

english, 2017

33

Genomic landscape of epithelium with low-grade atypia on gastric cancer after Helicobacter pylori eradiation therapy

Masuda, Kazuhiko, Urabe, Yuji, Ito, Masanori, Ono, Atsushi, Clair Nelson, Hayes, Nakamura, Koki, Kotachi, Takahiro, Boda, Tomoyuki, Tanaka, Shinji, Chayama, Kazuaki

Journal:

Journal of Gastroenterology

Year:

2019

Language:

english

File:

PDF, 5.74 MB

english, 2019

34

Regression of idiopathic thrombocytopenic purpura in a patient with eradication of hepatitis C virus by direct‐acting antivirals

Johira, Yusuke, Hatooka, Haruna, Mori, Nami, Fukuhara, Takayuki, Takaki, Shintaro, Shimomura, Yumi, Imamura, Michio, Nelson Hayes, C., Tsuji, Keiji, Chayama, Kazuaki

Journal:

Year:

2019

Language:

english

File:

PDF, 129 KB

english, 2019

35

Correction to: Genomic landscape of epithelium with low-grade atypia on gastric cancer after Helicobacter pylori eradication therapy

Masuda, Kazuhiko, Urabe, Yuji, Ito, Masanori, Ono, Atsushi, Clair Nelson, Hayes, Nakamura, Koki, Kotachi, Takahiro, Boda, Tomoyuki, Tanaka, Shinji, Chayama, Kazuaki

Journal:

Journal of Gastroenterology

Year:

2020

File:

PDF, 164 KB

2020

36

Real-word efficacy of sofosbuvir, velpatasvir plus ribavirin therapy for chronic hepatitis patients who failed to prior DAA therapy with NS5A-P32 deletion mutated HCV infection

Takaki, Shintaro, Imamura, Michio, Yamaguchi, Shuji, Fukuhara, Takayuki, Mori, Nami, Tsuji, Keiji, Ohya, Kazuki, Hayes, Clair Nelson, Aikata, Hiroshi, Chayama, Kazuaki

Journal:

Clinical Journal of Gastroenterology

Year:

2020

File:

PDF, 817 KB

2020

37

1105 COMPREHENSIVE CHARACTERIZATION OF THE GENOMIC LANDSCAPE OF NON-INVASIVE GASTRIC CANCER IN THE JAPANESE POPULATION USING TWO SUSCEPTIBILITY GENES

Nakamura, Koki, Urabe, Yuji, Kagemoto, Kenich, Ono, Atsushi, Nelson, Hayes C., Oka, Shiro, Tanaka, Shinji, Chayama, Kazuaki

Journal:

Gastroenterology

Year:

2020

File:

PDF, 138 KB

2020

38

Liver fibrosis assessments using FibroScan, virtual-touch tissue quantification, the FIB-4 index, and mac-2 binding protein glycosylation isomer levels compared with pathological findings of liver resection specimens in patients with hepatitis C infection

Ueda, Naoyuki, Kawaoka, Tomokazu, Imamura, Michio, Aikata, Hiroshi, Nakahara, Takashi, Murakami, Eisuke, Tsuge, Masataka, Hiramatsu, Akira, Hayes, C. Nelson, Yokozaki, Michiya, Chayama, Kazuaki

Journal:

BMC Gastroenterology

Year:

2020

File:

PDF, 1.12 MB

2020

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